Selection, Transmission, and Reversion of an Antigen-Processing Cytotoxic T-Lymphocyte Escape Mutation in Human Immunodeficiency Virus Type 1 Infection

Numerous studies now support that human immunodeficiency virus type 1 (HIV-1) evolution is influenced by immune selection pressure, with population studies showing an association between specific HLA alleles and mutations within defined cytotoxic T-lymphocyte epitopes. Here we combine sequence data...

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Main Authors: Allen, Todd M., Altfeld, Marcus, Yu, Xu G., O'Sullivan, Kristin M., Lichterfeld, Mathias, Le Gall, Sylvie, John, Mina, Mothe, Bianca R., Lee, Paul K., Kalife, Elizabeth T., Cohen, Daniel E., Freedberg, Kenneth A., Strick, Daryld A., Johnston, Mary N., Sette, Alessandro, Rosenberg, Eric S., Mallal, Simon A., Goulder, Philip J. R., Brander, Christian, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC421658/
https://ncbi.nlm.nih.gov/pubmed/15194783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.13.7069-7078.2004
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