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Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships

With the widespread use of O-alkoxyresorufin dealkylation assays since the 1990s, thousands of inhibitors of cytochrome P450 family 1 enzymes (P450s 1A1, 1A2, and 1B1) have been identified and studied. Generally, planar polycyclic molecules such as polycyclic aromatic hydrocarbons, stilbenoids, and...

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Autors principals: Liu, Jiawang, Sridhar, Jayalakshmi, Foroozesh, Maryam
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216474/
https://ncbi.nlm.nih.gov/pubmed/24287985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules181214470
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