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Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

The majority of trait-associated loci discovered through genome-wide association studies are located outside of known protein coding regions. Consequently, it is difficult to ascertain the mechanism underlying these variants and to pinpoint the causal alleles. Expression quantitative trait loci (eQT...

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Detalhes bibliográficos
Main Authors: Li, Qiyuan, Stram, Alexander, Chen, Constance, Kar, Siddhartha, Gayther, Simon, Pharoah, Paul, Haiman, Christopher, Stranger, Barbara, Kraft, Peter, Freedman, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215106/
https://ncbi.nlm.nih.gov/pubmed/24907074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu228
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