‘N-of-1-pathways’ unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine

BACKGROUND: The emergence of precision medicine allowed the incorporation of individual molecular data into patient care. Indeed, DNA sequencing predicts somatic mutations in individual patients. However, these genetic features overlook dynamic epigenetic and phenotypic response to therapy. Meanwhil...

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Detalhes bibliográficos
Main Authors: Gardeux, Vincent, Achour, Ikbel, Li, Jianrong, Maienschein-Cline, Mark, Li, Haiquan, Pesce, Lorenzo, Parinandi, Gurunadh, Bahroos, Neil, Winn, Robert, Foster, Ian, Garcia, Joe G N, Lussier, Yves A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Research and Applications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215042/
https://ncbi.nlm.nih.gov/pubmed/25301808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2013-002519
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