Convergent downstream candidate mechanisms of independent intergenic polymorphisms between co-classified diseases implicate epistasis among noncoding elements()

Eighty percent of DNA outside protein coding regions was shown biochemically functional by the ENCODE project, enabling studies of their interactions. Studies have since explored how convergent downstream mechanisms arise from independent genetic risks of one complex disease. However, the cross-talk...

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Detalhes bibliográficos
Publicado no:Pac Symp Biocomput
Main Authors: Han, Jiali, Li, Jianrong, Achour, Ikbel, Pesce, Lorenzo, Foster, Ian, Li, Haiquan, Lussier, Yves A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730078/
https://ncbi.nlm.nih.gov/pubmed/29218911
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