The Membrane Attack Complex in Aging Human Choriocapillaris: Relationship to Macular Degeneration and Choroidal Thinning

Age-related macular degeneration (AMD) is a common disease that can result in severe visual impairment. Abnormal regulation of the complement system has been implicated in its pathogenesis, and CFH polymorphisms contribute substantially to risk. How these polymorphisms exert their effects is poorly...

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Hlavní autoři: Mullins, Robert F., Schoo, Desi P., Sohn, Elliott H., Flamme-Wiese, Miles J., Workamelahu, Grefachew, Johnston, Rebecca M., Wang, Kai, Tucker, Budd A., Stone, Edwin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2014
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215023/
https://ncbi.nlm.nih.gov/pubmed/25204844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.07.017
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