The Membrane Attack Complex in Aging Human Choriocapillaris: Relationship to Macular Degeneration and Choroidal Thinning

Age-related macular degeneration (AMD) is a common disease that can result in severe visual impairment. Abnormal regulation of the complement system has been implicated in its pathogenesis, and CFH polymorphisms contribute substantially to risk. How these polymorphisms exert their effects is poorly...

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Autors principals: Mullins, Robert F., Schoo, Desi P., Sohn, Elliott H., Flamme-Wiese, Miles J., Workamelahu, Grefachew, Johnston, Rebecca M., Wang, Kai, Tucker, Budd A., Stone, Edwin M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2014
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215023/
https://ncbi.nlm.nih.gov/pubmed/25204844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.07.017
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