The Membrane Attack Complex in Aging Human Choriocapillaris: Relationship to Macular Degeneration and Choroidal Thinning

Age-related macular degeneration (AMD) is a common disease that can result in severe visual impairment. Abnormal regulation of the complement system has been implicated in its pathogenesis, and CFH polymorphisms contribute substantially to risk. How these polymorphisms exert their effects is poorly...

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Detalhes bibliográficos
Main Authors: Mullins, Robert F., Schoo, Desi P., Sohn, Elliott H., Flamme-Wiese, Miles J., Workamelahu, Grefachew, Johnston, Rebecca M., Wang, Kai, Tucker, Budd A., Stone, Edwin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215023/
https://ncbi.nlm.nih.gov/pubmed/25204844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.07.017
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