Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury

Age-related macular degeneration (AMD) is a common, blinding disease associated with increased complement system activity. Eyes with AMD show elevated accumulation of the membrane attack complex (MAC) in the choriocapillaris and degeneration of macular choriocapillaris endothelial cells (ECs). Thus,...

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Опубликовано в: :Sci Rep
Главные авторы: Zeng, Shemin, Wen, Kuo-Kuang, Workalemahu, Grefachew, Sohn, Elliott H., Wu, Meng, Chirco, Kathleen R., Flamme-Wiese, Miles J., Liu, Xiuying, Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127142/
https://ncbi.nlm.nih.gov/pubmed/30190604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31846-z
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