Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury

Age-related macular degeneration (AMD) is a common, blinding disease associated with increased complement system activity. Eyes with AMD show elevated accumulation of the membrane attack complex (MAC) in the choriocapillaris and degeneration of macular choriocapillaris endothelial cells (ECs). Thus,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zeng, Shemin, Wen, Kuo-Kuang, Workalemahu, Grefachew, Sohn, Elliott H., Wu, Meng, Chirco, Kathleen R., Flamme-Wiese, Miles J., Liu, Xiuying, Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127142/
https://ncbi.nlm.nih.gov/pubmed/30190604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31846-z
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