Evaluation of serum and ocular levels of membrane attack complex and C-reactive protein in CFH-genotyped human donors

BACKGROUND: There is a considerable body of evidence demonstrating a link between the membrane attack complex (MAC) and age-related macular degeneration (AMD), and between C-reactive protein (CRP) and AMD. Both the MAC and the monomeric form of CRP (mCRP) accumulate within the choriocapillaris in AM...

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Vydáno v:Eye (Lond)
Hlavní autoři: Chirco, Kathleen R., Flamme-Wiese, Miles J., Wiley, Jill S., Potempa, Lawrence A., Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224589/
https://ncbi.nlm.nih.gov/pubmed/30013157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41433-018-0170-8
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