Gene Profiling of Postnatal Mfrp(rd6) Mutant Eyes Reveals Differential Accumulation of Prss56, Visual Cycle and Phototransduction mRNAs

Mutations in the membrane frizzled-related protein (MFRP/Mfrp) gene, specifically expressed in the retinal pigment epithelium (RPE) and ciliary body, cause nanophthalmia or posterior microphthalmia with retinitis pigmentosa in humans, and photoreceptor degeneration in mice. To better understand MFRP...

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Autors principals: Soundararajan, Ramani, Won, Jungyeon, Stearns, Timothy M., Charette, Jeremy R., Hicks, Wanda L., Collin, Gayle B., Naggert, Jürgen K., Krebs, Mark P., Nishina, Patsy M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214712/
https://ncbi.nlm.nih.gov/pubmed/25357075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110299
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