Genetic modifier loci of mouse Mfrp(rd6) identified by quantitative trait locus analysis

The identification of genes that modify pathological ocular phenotypes in mouse models may improve our understanding of disease mechanisms and lead to new treatment strategies. Here, we identify modifier loci affecting photoreceptor cell loss in homozygous Mfrp(rd6) mice, which exhibit a slowly prog...

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Autori principali: Won, Jungyeon, Charette, Jeremy R., Philip, Vivek M., Stearns, Timothy M., Zhang, Weidong, Naggert, Jürgen K., Krebs, Mark P., Nishina, Patsy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153418/
https://ncbi.nlm.nih.gov/pubmed/24200520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.10.020
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