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Meckelin Is Necessary for Photoreceptor Intraciliary Transport and Outer Segment Morphogenesis

PURPOSE. Cilia, complex structures found ubiquitously in most vertebrate cells, serve a variety of functions ranging from cell and fluid movement, cell signaling, tissue homeostasis, to sensory perception. Meckelin is a component of ciliary and cell membranes and is encoded by Tmem67 (Mks3). In this...

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Detalhes bibliográficos
Main Authors: Collin, Gayle B., Won, Jungyeon, Hicks, Wanda L., Cook, Susan A., Nishina, Patsy M., Naggert, Jürgen K.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317434/
https://ncbi.nlm.nih.gov/pubmed/22247471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8766
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