Genetic modifier loci of mouse Mfrp(rd6) identified by quantitative trait locus analysis

The identification of genes that modify pathological ocular phenotypes in mouse models may improve our understanding of disease mechanisms and lead to new treatment strategies. Here, we identify modifier loci affecting photoreceptor cell loss in homozygous Mfrp(rd6) mice, which exhibit a slowly prog...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Won, Jungyeon, Charette, Jeremy R., Philip, Vivek M., Stearns, Timothy M., Zhang, Weidong, Naggert, Jürgen K., Krebs, Mark P., Nishina, Patsy M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153418/
https://ncbi.nlm.nih.gov/pubmed/24200520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.10.020
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