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Structural mechanisms of human RecQ helicases WRN and BLM
The RecQ family DNA helicases Werner syndrome protein (WRN) and Bloom syndrome protein (BLM) play a key role in protecting the genome against deleterious changes. In humans, mutations in these proteins lead to rare genetic diseases associated with cancer predisposition and accelerated aging. WRN and...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
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Frontiers Media S.A.
2014
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4212688/ https://ncbi.nlm.nih.gov/pubmed/25400656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00366 |
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