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Convenient synthesis of N1-substituted orotic acid derivatives

A convenient and efficient method for the synthesis of N1-substituted orotic acid derivatives is reported. The synthetic route utilizes substituted maleimide as synthetic intermediate and takes only four simple steps from readily available starting materials. As a result, orotic acid derivatives wit...

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Hlavní autoři: Bowler, Jeannette T., Clausen, Caitlin R., Blackburn, Daniel J., Wu, Weiming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210862/
https://ncbi.nlm.nih.gov/pubmed/25364061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.10.005
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