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Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging

Age-related skeletal muscle dysfunction is a leading cause of morbidity that affects up to half the population aged 80 or greater. Here we tested the effects of increased mitochondrial antioxidant activity on age-dependent skeletal muscle dysfunction using transgenic mice with targeted overexpressio...

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Autors principals: Umanskaya, Alisa, Santulli, Gaetano, Xie, Wenjun, Andersson, Daniel C., Reiken, Steven R., Marks, Andrew R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210348/
https://ncbi.nlm.nih.gov/pubmed/25288763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412754111
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