Stress-induced increase in skeletal muscle force requires protein kinase A phosphorylation of the ryanodine receptor

Enhancement of contractile force (inotropy) occurs in skeletal muscle following neuroendocrine release of catecholamines and activation of muscle β-adrenergic receptors. Despite extensive study, the molecular mechanism underlying the inotropic response in skeletal muscle is not well understood. Here...

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Autori principali: Andersson, Daniel C, Betzenhauser, Matthew J, Reiken, Steven, Umanskaya, Alisa, Shiomi, Takayuki, Marks, Andrew R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
Soggetti:
Skeletal Muscle and Exercise
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533199/
https://ncbi.nlm.nih.gov/pubmed/23070698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.237925
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