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Role of CaMKIIδ phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure

The force frequency relationship (FFR), first described by Bowditch 139 years ago as the observation that myocardial contractility increases proportionally with increasing heart rate, is an important mediator of enhanced cardiac output during exercise. Individuals with heart failure have defective p...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Kushnir, Alexander, Shan, Jian, Betzenhauser, Matthew J., Reiken, Steven, Marks, Andrew R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890457/
https://ncbi.nlm.nih.gov/pubmed/20479242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005843107
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