Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers

Oncolytic virotherapy is a growing treatment modality that uses replicating viruses as selective antineoplastic agents. Safety and efficacy considerations dictate that an ideal oncolytic agent would discriminate between normal and cancer cells on the basis of common genetic abnormalities in human ca...

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Hlavní autoři: Lin, Yuan, Zhang, Haipeng, Liang, Jiankai, Li, Kai, Zhu, Wenbo, Fu, Liwu, Wang, Fang, Zheng, Xiaoke, Shi, Huijuan, Wu, Sihan, Xiao, Xiao, Chen, Lijun, Tang, Lipeng, Yan, Min, Yang, Xiaoxiao, Tan, Yaqian, Qiu, Pengxin, Huang, Yijun, Yin, Wei, Su, Xinwen, Hu, Haiyan, Hu, Jun, Yan, Guangmei
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210284/
https://ncbi.nlm.nih.gov/pubmed/25288727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408759111
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