Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers

Oncolytic virotherapy is a growing treatment modality that uses replicating viruses as selective antineoplastic agents. Safety and efficacy considerations dictate that an ideal oncolytic agent would discriminate between normal and cancer cells on the basis of common genetic abnormalities in human ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Yuan, Zhang, Haipeng, Liang, Jiankai, Li, Kai, Zhu, Wenbo, Fu, Liwu, Wang, Fang, Zheng, Xiaoke, Shi, Huijuan, Wu, Sihan, Xiao, Xiao, Chen, Lijun, Tang, Lipeng, Yan, Min, Yang, Xiaoxiao, Tan, Yaqian, Qiu, Pengxin, Huang, Yijun, Yin, Wei, Su, Xinwen, Hu, Haiyan, Hu, Jun, Yan, Guangmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210284/
https://ncbi.nlm.nih.gov/pubmed/25288727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408759111
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