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Designer HF-Based Fluorination Reagent: Highly Regioselective Synthesis of Fluoroalkenes and gem-Difluoromethylene Compounds from Alkynes

[Image: see text] Hydrogen fluoride (HF) and selected nonbasic and weakly coordinating (toward cationic metal) hydrogen-bond acceptors (e.g., DMPU) can form stable complexes through hydrogen bonding. The DMPU/HF complex is a new nucleophilic fluorination reagent that has high acidity and is compatib...

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Autori principali: Okoromoba, Otome E., Han, Junbin, Hammond, Gerald B., Xu, Bo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210154/
https://ncbi.nlm.nih.gov/pubmed/25260170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508369z
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