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Synthesis of gem-difluoromethylenated analogues of boronolide

The straightforward synthesis of four gem-difluoromethylenated analogues 4–7 of boronolide is described. The key steps of the synthesis include the concise preparation of the key intermediates 12a–b through the indium-mediated gem-difluoropropargylation of aldehyde 9 with the fluorine-containing bui...

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書誌詳細
主要な著者: Lin, Jing, Qiu, Xiao-Long, Qing, Feng-Ling
フォーマット: Artigo
言語:Inglês
出版事項: Beilstein-Institut 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874314/
https://ncbi.nlm.nih.gov/pubmed/20502653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.6.37
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