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Synthesis of constrained analogues of tryptophan

A Lewis acid-catalysed diastereoselective [4 + 2] cycloaddition of vinylindoles and methyl 2-acetamidoacrylate, leading to methyl 3-acetamido-1,2,3,4-tetrahydrocarbazole-3-carboxylate derivatives, is described. Treatment of the obtained cycloadducts under hydrolytic conditions results in the prepara...

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Bibliografiske detaljer
Udgivet i:Beilstein J Org Chem
Main Authors: Rossi, Elisabetta, Pirovano, Valentina, Negrato, Marco, Abbiati, Giorgio, Dell’Acqua, Monica
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661003/
https://ncbi.nlm.nih.gov/pubmed/26664620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.216
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