Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971

[Image: see text] The imaging of translocator 18 kDa protein (TSPO) in living human brain with radioligands by positron emission tomography (PET) has become an important means for the study of neuroinflammatory conditions occurring in several neuropsychiatric disorders. The widely used prototypical...

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Autors principals: Zanotti-Fregonara, Paolo, Zhang, Yi, Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Fujita, Masahiro, Sbardella, Gianluca, Castellano, Sabrina, Taliani, Sabrina, Martini, Claudia, Innis, Robert B., Da Settimo, Federico, Pike, Victor W.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210126/
https://ncbi.nlm.nih.gov/pubmed/25123416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500138n
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