Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971

[Image: see text] The imaging of translocator 18 kDa protein (TSPO) in living human brain with radioligands by positron emission tomography (PET) has become an important means for the study of neuroinflammatory conditions occurring in several neuropsychiatric disorders. The widely used prototypical...

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Main Authors: Zanotti-Fregonara, Paolo, Zhang, Yi, Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Fujita, Masahiro, Sbardella, Gianluca, Castellano, Sabrina, Taliani, Sabrina, Martini, Claudia, Innis, Robert B., Da Settimo, Federico, Pike, Victor W.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210126/
https://ncbi.nlm.nih.gov/pubmed/25123416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500138n
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