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An extended Shine–Dalgarno sequence in mRNA functionally bypasses a vital defect in initiator tRNA
Initiator tRNAs are special in their direct binding to the ribosomal P-site due to the hallmark occurrence of the three consecutive G-C base pairs (3GC pairs) in their anticodon stems. How the 3GC pairs function in this role, has remained unsolved. We show that mutations in either the mRNA or 16S rR...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210040/ https://ncbi.nlm.nih.gov/pubmed/25246575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411637111 |
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