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Rapid formylation of the cellular initiator tRNA population makes a crucial contribution to its exclusive participation at the step of initiation
Initiator tRNAs (i-tRNAs) possess highly conserved three consecutive GC base pairs (GC/GC/GC, 3GC pairs) in their anticodon stems. Additionally, in bacteria and eukaryotic organelles, the amino acid attached to i-tRNA is formylated by Fmt to facilitate its targeting to 30S ribosomes. Mutations in GC...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6393288/ https://ncbi.nlm.nih.gov/pubmed/30608556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1310 |
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