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Crucial contribution of the multiple copies of the initiator tRNA genes in the fidelity of tRNA(fMet) selection on the ribosomal P-site in Escherichia coli

The accuracy of the initiator tRNA (tRNA(fMet)) selection in the ribosomal P-site is central to the fidelity of protein synthesis. A highly conserved occurrence of three consecutive G–C base pairs in the anticodon stem of tRNA(fMet) contributes to its preferential selection in the P-site. In a genet...

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Autori principali: Kapoor, Suman, Das, Gautam, Varshney, Umesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017606/
https://ncbi.nlm.nih.gov/pubmed/20798174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq760
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