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MUC1 oncoprotein activates the IκB kinase β complex and constitutive NF-κB signalling
Nuclear factor-κB (NF-κB) is constitutively activated in diverse human malignancies by mechanisms that are not understood(1,2). The MUC1 oncoprotein is aberrantly overexpressed by most human carcinomas and, similarly to NF-κB, blocks apoptosis and induces transformation(3–6). This study demonstrates...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209910/ https://ncbi.nlm.nih.gov/pubmed/18037881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1661 |
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