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MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage
The nonreceptor c-Abl tyrosine kinase binds to cytosolic 14-3-3 proteins and is targeted to the nucleus in the apoptotic response to DNA damage. The MUC1 oncoprotein is overexpressed by most human carcinomas and blocks the induction of apoptosis by genotoxic agents. Using human carcinoma cells with...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2006
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1553184/ https://ncbi.nlm.nih.gov/pubmed/16888623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601263 |
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