Immunoglobulin Free Light Chains and GAGs Mediate Multiple Myeloma Extracellular Vesicles Uptake and Secondary NfκB Nuclear Translocation

Multiple myeloma (MM) is a hematological malignancy caused by a microenviromentally aided persistence of plasma cells in the bone marrow. Monoclonal plasma cells often secrete high amounts of immunoglobulin free light chains (FLCs) that could induce tissue damage. Recently, we showed that FLCs are i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Di Noto, Giuseppe, Chiarini, Marco, Paolini, Lucia, Mazzoldi, Elena Laura, Giustini, Viviana, Radeghieri, Annalisa, Caimi, Luigi, Ricotta, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209816/
https://ncbi.nlm.nih.gov/pubmed/25386176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00517
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados