RELATIONSHIP BETWEEN ELEVATED IMMUNOGLOBULIN FREE LIGHT CHAIN AND THE PRESENCE OF IgH TRANSLOCATIONS IN MULTIPLE MYELOMA

Elevated immunoglobulin free light chain (FLC) level and abnormal FLC ratio is commonly seen in multiple myeloma (MM) and have prognostic implications. We hypothesized that presence of IgH translocations leads to unbalanced production of light chains and more extreme abnormalities of FLC and may exp...

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Auteurs principaux: Kumar, S., Zhang, L., Dispenzieri, A., Van Wier, S., Katzmann, J.A., Snyder, M., Blood, E., DeGoey, R., Henderson, K., Kyle, R.A., Bradwell, A.R., Greipp, P.R., Rajkumar, S.V., Fonseca, R
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558529/
https://ncbi.nlm.nih.gov/pubmed/20520636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.128
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