RELATIONSHIP BETWEEN ELEVATED IMMUNOGLOBULIN FREE LIGHT CHAIN AND THE PRESENCE OF IgH TRANSLOCATIONS IN MULTIPLE MYELOMA

Elevated immunoglobulin free light chain (FLC) level and abnormal FLC ratio is commonly seen in multiple myeloma (MM) and have prognostic implications. We hypothesized that presence of IgH translocations leads to unbalanced production of light chains and more extreme abnormalities of FLC and may exp...

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Detalhes bibliográficos
Main Authors: Kumar, S., Zhang, L., Dispenzieri, A., Van Wier, S., Katzmann, J.A., Snyder, M., Blood, E., DeGoey, R., Henderson, K., Kyle, R.A., Bradwell, A.R., Greipp, P.R., Rajkumar, S.V., Fonseca, R
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558529/
https://ncbi.nlm.nih.gov/pubmed/20520636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.128
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