Suppression of uninvolved immunoglobulins defined by heavy/light chain pair suppression is a risk factor for progression of MGUS

We hypothesized that the suppression of uninvolved immunoglobulin in monoclonal gammopathy of undetermined significance (MGUS) as detected by suppression of the isotype-specific heavy and light chain (HLC-pair suppression) increases the risk of progression to malignancy. This approach required quant...

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Detalhes bibliográficos
Main Authors: Katzmann, JA, Clark, R, Kyle, RA, Larson, DR, Therneau, TM, Melton, LJ, Benson, JT, Colby, CL, Dispenzieri, A, Landgren, O, Kumar, S, Bradwell, AR, Cerhan, JR, Rajkumar, SV
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691011/
https://ncbi.nlm.nih.gov/pubmed/22781594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.189
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