Exacerbated experimental arthritis in Wiskott–Aldrich syndrome protein deficiency: Modulatory role of regulatory B cells

Patients deficient in the cytoskeletal regulator Wiskott–Aldrich syndrome protein (WASp) are predisposed to varied autoimmunity, suggesting it has an important controlling role in participating cells. IL-10-producing regulatory B (Breg) cells are emerging as important mediators of immunosuppressive...

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Detalhes bibliográficos
Main Authors: Bouma, Gerben, Carter, Natalie A, Recher, Mike, Malinova, Dessislava, Adriani, Marsilio, Notarangelo, Luigi D, Burns, Siobhan O, Mauri, Claudia, Thrasher, Adrian J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Immunomodulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209796/
https://ncbi.nlm.nih.gov/pubmed/24945741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344245
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