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Dextromethorphan Mediated Bitter Taste Receptor Activation in the Pulmonary Circuit Causes Vasoconstriction

Activation of bitter taste receptors (T2Rs) in human airway smooth muscle cells leads to muscle relaxation and bronchodilation. This finding led to our hypothesis that T2Rs are expressed in human pulmonary artery smooth muscle cells and might be involved in regulating the vascular tone. RT-PCR was p...

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Detalhes bibliográficos
Main Authors: Upadhyaya, Jasbir D., Singh, Nisha, Sikarwar, Anurag S., Chakraborty, Raja, Pydi, Sai P., Bhullar, Rajinder P., Dakshinamurti, Shyamala, Chelikani, Prashen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207743/
https://ncbi.nlm.nih.gov/pubmed/25340739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110373
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