New Insights into Structural Determinants for Prostanoid Thromboxane A2 Receptor- and Prostacyclin Receptor-G Protein Coupling

G protein-coupled receptors (GPCRs) interact with heterotrimeric G proteins and initiate a wide variety of signaling pathways. The molecular nature of GPCR-G protein interactions in the clinically important thromboxane A2 (TxA(2)) receptor (TP) and prostacyclin (PGI(2)) receptor (IP) is poorly under...

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Hlavní autoři: Chakraborty, Raja, Pydi, Sai Prasad, Gleim, Scott, Bhullar, Rajinder Pal, Hwa, John, Dakshinamurti, Shyamala, Chelikani, Prashen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554117/
https://ncbi.nlm.nih.gov/pubmed/23109431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00725-12
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