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Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor
G protein-coupled receptors (GPCRs) show some level of basal activity even in the absence of an agonist, a phenomenon referred to as constitutive activity. Such constitutive activity in GPCRs is known to have important pathophysiological roles in human disease. The thromboxane A2 receptor (TP) is a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900440/ https://ncbi.nlm.nih.gov/pubmed/24465800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085937 |
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