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Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics

The pharmacokinetics and selected pharmacodynamic responses to methylprednisolone were investigated in six men and six premenopausal women after a dose of 0.6 mg/kg ideal body weight. Women (luteal phase) exhibited a greater methylprednisolone clearance (0.45 versus 0.29 L/hr/kg) and shorter elimina...

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Bibliografiske detaljer
Main Authors: Lew, Kim H., Ludwig, Elizabeth A., Milad, Mark A., Donovan, Kathleen, Middleton, Elliott, Ferry, James J., Jusko, William J.
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207261/
https://ncbi.nlm.nih.gov/pubmed/8222483
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