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From molecular signatures to predictive biomarkers: modeling disease pathophysiology and drug mechanism of action

Omics profiling significantly expanded the molecular landscape describing clinical phenotypes. Association analysis resulted in first diagnostic and prognostic biomarker signatures entering clinical utility. However, utilizing Omics for deepening our understanding of disease pathophysiology, and fur...

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Détails bibliographiques
Auteurs principaux: Heinzel, Andreas, Perco, Paul, Mayer, Gert, Oberbauer, Rainer, Lukas, Arno, Mayer, Bernd
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207010/
https://ncbi.nlm.nih.gov/pubmed/25364744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00037
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