Vascular endothelial growth factor A as predictive marker for mTOR inhibition in relapsing high-grade serous ovarian cancer

BACKGROUND: Development of resistance against first line drug therapy including cisplatin and paclitaxel in high-grade serous ovarian cancer (HGSOC) presents a major challenge. Identifying drug candidates breaking resistance, ideally combined with predictive biomarkers allowing precision use are nee...

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Veröffentlicht in:BMC Syst Biol
Hauptverfasser: Andorfer, Peter, Heuwieser, Alexander, Heinzel, Andreas, Lukas, Arno, Mayer, Bernd, Perco, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836190/
https://ncbi.nlm.nih.gov/pubmed/27090655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0278-z
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