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From molecular signatures to predictive biomarkers: modeling disease pathophysiology and drug mechanism of action

Omics profiling significantly expanded the molecular landscape describing clinical phenotypes. Association analysis resulted in first diagnostic and prognostic biomarker signatures entering clinical utility. However, utilizing Omics for deepening our understanding of disease pathophysiology, and fur...

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Detalhes bibliográficos
Main Authors: Heinzel, Andreas, Perco, Paul, Mayer, Gert, Oberbauer, Rainer, Lukas, Arno, Mayer, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207010/
https://ncbi.nlm.nih.gov/pubmed/25364744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00037
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