Markers of T Cell Infiltration and Function Associate with Favorable Outcome in Vascularized High-Grade Serous Ovarian Carcinoma

BACKGROUND: When T cells infiltrate the tumor environment they encounter a myriad of metabolic stressors including hypoxia. Overcoming the limitations imposed by an inadequate tumor vasculature that contributes to these stressors may be a crucial step to immune cells mounting an effective anti-tumor...

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Auteurs principaux: Townsend, Katelin N., Spowart, Jaeline E., Huwait, Hassan, Eshragh, Sima, West, Nathan R., Elrick, Mary A., Kalloger, Steve E., Anglesio, Michael, Watson, Peter H., Huntsman, David G., Lum, Julian J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871161/
https://ncbi.nlm.nih.gov/pubmed/24376535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082406
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