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Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation
FGF applied as a single growth factor to quiescent mouse fibroblasts induces a round of DNA replication, however continuous stimulation results in arrest in the G1 phase of the next cell cycle. We hypothesized that FGF stimulation induces the establishment of cell memory, which prevents the prolifer...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205782/ https://ncbi.nlm.nih.gov/pubmed/24375433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24731 |
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