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Sustained inhibition of proliferative response after transient FGF stimulation is mediated by interleukin 1 signaling

Transient FGF stimulation of various cell types results in FGF memory – a sustained blockage of efficient proliferative response to FGF and other growth factors. FGF memory establishment requires HDAC activity, indicating its epigenetic character. FGF treatment stimulates proinflammatory NFκB signal...

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Bibliografiske detaljer
Udgivet i:J Cell Physiol
Main Authors: Poole, Ashleigh, Kacer, Doreen, Cooper, Emily, Tarantini, Francesca, Prudovsky, Igor
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397993/
https://ncbi.nlm.nih.gov/pubmed/26218437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25111
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