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Sustained inhibition of proliferative response after transient FGF stimulation is mediated by interleukin 1 signaling

Transient FGF stimulation of various cell types results in FGF memory – a sustained blockage of efficient proliferative response to FGF and other growth factors. FGF memory establishment requires HDAC activity, indicating its epigenetic character. FGF treatment stimulates proinflammatory NFκB signal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Physiol
Hauptverfasser: Poole, Ashleigh, Kacer, Doreen, Cooper, Emily, Tarantini, Francesca, Prudovsky, Igor
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397993/
https://ncbi.nlm.nih.gov/pubmed/26218437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25111
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