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Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation

FGF applied as a single growth factor to quiescent mouse fibroblasts induces a round of DNA replication, however continuous stimulation results in arrest in the G1 phase of the next cell cycle. We hypothesized that FGF stimulation induces the establishment of cell memory, which prevents the prolifer...

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Sonraí Bibleagrafaíochta
Main Authors: Poole, Ashleigh, Knowland, Nicholas, Cooper, Emily, Cole, Rebecca, Wang, Hongchuan, Booth, Lucas, Kacer, Doreen, Tarantini, Francesca, Friesel, Robert, Prudovsky, Igor
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205782/
https://ncbi.nlm.nih.gov/pubmed/24375433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24731
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