Thrombin induces rapid PAR1-mediated non-classical FGF1 release

Thrombin induces cell proliferation and migration during vascular injury. We report that thrombin rapidly stimulated expression and release of the pro-angiogenic polypeptide fibroblast growth factor 1 (FGF1). Thrombin failed to induce FGF1 release from protease activated receptor 1 (PAR1) null fibro...

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Détails bibliographiques
Auteurs principaux: Duarte, Maria, Kolev, Vihren, Soldi, Raffaella, Kirov, Alexander, Graziani, Irene, Oliveira, Silvia Marta, Kacer, Doreen, Friesel, Robert, Maciag, Thomas, Prudovsky, Igor
Format: Artigo
Langue:Inglês
Publié: 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698861/
https://ncbi.nlm.nih.gov/pubmed/17027650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.107
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