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Conformational cycle and ion-coupling mechanism of the Na(+)/hydantoin transporter Mhp1
Ion-dependent transporters of the LeuT-fold couple the uptake of physiologically essential molecules to transmembrane ion gradients. Defined by a conserved 5-helix inverted repeat that encodes common principles of ion and substrate binding, the LeuT-fold has been captured in outward-facing, occluded...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205665/ https://ncbi.nlm.nih.gov/pubmed/25267652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410431111 |
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