Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis

Intestinal fibrostenosis is among the hallmarks of severe Crohn’s disease. Patients with certain TNFSF15 (gene name for TL1A) variants over-express TL1A and have a higher risk of developing strictures in the small intestine. Additionally, sustained Tl1a expression in mice leads to small and large in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Shih, David Q, Zheng, Libo, Zhang, Xiaolan, Zhang, Hong, Kanazawa, Yoshitake, Ichikawa, Ryan, Wallace, Kori L, Chen, Jeremy, Pothoulakis, Charalabos, Koon, Hon W, Targan, Stephan R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205266/
https://ncbi.nlm.nih.gov/pubmed/24850426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.37
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia